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Rybelsus® (semaglutide) tablets

Rybelsus® (semaglutide) tablets is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.

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Pharmacology

Glycemic Control Trials

Specific Population Studies

  • Cardiovascular Safety of Rybelsus® vs. Placebo (PIONEER 6 Study)

    This video discusses the trial-design and outcomes of the PIONEER 6 study. PIONEER 6 was a phase 3a, randomized, double-blind, multinational trial that enrolled 3183 adult patients (age ≥50 years) with type 2 diabetes. Eligible patients were at least 50 years of age with established cardiovascular (CV) disease or chronic kidney disease, or patients were at least 60 years of age with at least one CV risk factor.

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